Orthopaedics and Trauma
Volume 23, Issue 2 , Pages 117-121, April 2009

Is infection inevitable in some arthroplasty patients?

RJ Langley PhD is a Post-doctoral Researcher, in the Section of Orthopaedic and Trauma Surgery, Ninewells Hospital and Medical School, Dundee, UK

DI Rowley FRCS is a Professor in Orthopaedic and Trauma Surgery Department, Ninewells Hospital and Medical School, Dundee, UK

Abstract 

Infection is a rare complication of arthroplasty surgery, yet the consequences of such an event lead to significant costs both in terms of finance and patient morbidity. This review describes the current literature examining a possible genetic link between post-surgical infections, cytokines and polymorphisms in the gene encoding the acute phase protein mannose binding lectin.

Keywords: arthroplasty, cytokines, genetic, infection

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PII: S1877-1327(08)00199-1

doi:10.1016/j.mporth.2008.12.004

Orthopaedics and Trauma
Volume 23, Issue 2 , Pages 117-121, April 2009