Orthopaedics and Trauma
Volume 23, Issue 4 , Pages 240-247, August 2009

(iii) The management of soft-tissue sarcomas

Thomas B Beckingsale MSc(Durham) MBBS(Newcastle) MRCS(England) is a Specialist Registrar Orthopaedics and Trauma at Sunderland Royal Hospital, Sunderland, UK

Craig H Gerrand MBChB FRCS Trauma and Orth(Edinburgh) MD is a Consultant in Orthopaedic Oncology and Honorary Senior Lecturer at Newcastle University, Northern Centre for Bone and Soft Tissue Tumours, Freeman Hospital, Newcastle upon Tyne, UK

Abstract 

Soft-tissue sarcomas are a heterogeneous group of malignant tumours of connective tissue. The investigation, diagnosis and treatment of these rare tumours should be co-ordinated by specialist multi-disciplinary teams. Here we discuss the surgical principles involved in the management of these tumours, and explore the literature on surgical margins and adjuvant treatment. The management of local and systemic recurrence and prognosis are discussed and the evidence base reviewed.

Keywords: chemotherapy, margins, radiotherapy, sarcoma, surgery

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PII: S1877-1327(09)00080-3

doi:10.1016/j.mporth.2009.05.004

Orthopaedics and Trauma
Volume 23, Issue 4 , Pages 240-247, August 2009